Informing Spectroscopists for Over 40 Years


Dmitry Gakamsky and Anna Gakamsky describe how fluorescence may be used to diagnose cataracts in human eye lenses. Further, it may also be able to grade cataracts and monitor the disease’s progress, which may help discover metabolic and ambient factors that influence the progress of the disease.

Edible bird’s nest (EBN) is a highly valued food, especially in China. Due to this, there is the potential to bulk out the EBN with artificial additives to receive a higher price. This article shows yet another way in which spectroscopy is used to detect adulteration of food and prevent fraud in a quick and cost-­effective manner.

Vince Palleschi takes a slightly different approach to reviewing the current state of laser-induced breakdown spectroscopy (LIBS). He puts the strengths and weaknesses of LIBS in context and gives some examples of industrial applications.

We all know how spectroscopy and other analytical technologies have played important roles in detecting fraud and in authentication. Paper collages, or photomontages, are part of the art market that is seeing much interest amongst collectors. It is difficult to detect forgeries just through expertise. The use of NIR imaging offers a number of ways to identify forgeries or authenticate the collage non-destructively; from determining the glue used to the revealing of printing on the back of the pieces or paper, which often have been taken from books and magazines.

Jars of honey

X-ray spectroscopy techniques have some advantages over other atomic spectroscopy techniques in the analysis of foods, for instance in not requiring significant sample preparation. Amongst these, TXRF has higher sensitivity and limits of detection in the ng range. The authors look at the analysis of a number of very different foods, including seafood, honey and vegetables.

This article demonstrates the capability of the near-field method to probe polymer microspheres within a protein matrix, and we present the first IRSR photothermal near-field Fourier transform infrared (FT-IR) spectrum from within an individual biological cell, which establishes the feasibility of hyperspectral mapping at sub-micrometre resolution in a practical timescale.

The CAL(AI)2DOSCOPE (Cryogenic Absorption/Luminescence Alignment Independent Alternative Intermittent Detection Optical µSCOPE) is a microspectrometer that was constructed with the aim to facilitate the correlated investigation of absorption and fluorescence emission properties of nanovolumic protein samples under modulatable actinic illumination.

Whilst the major components of food are usually non-fluorescent, many minor food components that affect its nutritive, compositional and technological quality are fluorescent. Given its sensitivity, ease of use and non-destructive nature, this makes it useful in many applications around monitoring food processing and in fundamental food research.

This article is is a fascinating look into the use of laser ablation inductively coupled plasma mass spectrometry in forensic examination of glass fragments. These are often associated with crime scenes and easily “attach” to any people near them. Thus, they can be used to link criminals to their crime and to provide information on where a glass fragment might have originated.

This article gives a most useful overview of the analysis and sequencing of nucleic acids by matrix-assisted laser desorption/ionisation mass spectrometry, which should interest all readers and may well serve as a useful tutorial article.