In Search of Biomarkers: Mass Spectrometry as a Tool for Discovery
Tuesday, October 26, 2010: 15:00 UTC
Mass spectrometry coupled with liquid chromatography is one of the most powerful techniques for biomarker discovery due to the attributes that these tools exhibit over other methods. Of these, perhaps the most important are the sensitivity and selectivity of the method, and the facile manner in which structural information can be determined. Evidence of this can be seen in the substantial adoption of these technologies for both metabolomic and proteomic analysis. The goals of these experiments are shifting, and it is no longer sufficient to identify potential biomarkers such as endogenous metabolites, peptides, and proteins, but these species must also be quantified at low endogenous concentrations. In order to meet these challenges, new instrumentation and workflows have been developed. In this webinar, hear from experts in the field about the challenges and solutions associated with the search for biomarkers and promising analytical solutions to address them.
- Strategies for simultaneous quantitative and qualitative data collection and interpretation
- What it means to control variability in samples and gain confidence in your biomarker discovery
- How statistical methods aid discovery in metabolomics
- How high definition mass spectrometry (HDMS) can redefine the limits of sensitivity for protein identification
Your presenters:
John P Shockcor
Director of Life Sciences Business Development
Waters Corporation
Director of Proteomics Business Operations
Waters Corporation
