The Thermo Scientific TSQ Fortis triple quadrupole mass spectrometer has Active Ion Management Plus, which enables high precision for every molecule type in complex matrices. Selected reaction monitoring capability with ion transmission efficiency is designed for simultaneous, reliable quantitation of all components in a complex matrix for high instrument throughput. It also has a novel ion optics design, which provides simple, tool-free maintenance. The Matrix Separator Ion Guide provides maximum robustness while minimising ion loss. Easy-to-use workflows offer efficiency without compromising data quality from sample injection to report generation. Intuitive drag-and-drop method editor software provides simple method development and operation through application-based templates.