SCIEX has launched its SWATH® data independent acquisition (DIA) technology for the new X500 series mass spectrometers, enabling it use on a routine system. SWATH Acquisition allows the simultaneous and comprehensive identification and quantification of virtually every detectable compound in a sample, from a single analysis. SWATH Acquisition has unique capabilities for quantitative accuracy, offering high reproducibility across multiple samples with wide dynamic range. The technology enables the creation of a permanent digital record of quantitative MS/MS data for the entire sample. Following the implementation of SWATH for proteomics research, this technology can be used in other fields, including forensics, food testing, environmental analysis and biologics.