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Ready-to-use mass spectrometric kit simplifies insulin bioanalysis workflows

Thermo Scientific’s new, ready-to-use InsuQuant mass spectrometric immunoassay kit incorporates all the necessary reagents and consumables needed in the pre-analytical stage of the LC-MS workflow in a convenient, easy-to-use platform. The kit is designed to eliminate the need for researchers to make buffers and match reagents, thus saving resources and reducing the risk of human errors in complex protocols, which can be costly and impact productivity. It uses proprietary microcolumn technology to enable advanced detection of endogenous insulin and its exogenous analogues in the tip of a pipette, while also reducing background and improving reproducibility. The mass spectrometric immunoassay (MSIA) methodology has demonstrated pg mL–1 levels of detection while yielding simultaneous qualitative and quantitative data from complex biological matrices, making it well suited for use with plasma.

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