The Thermo Scientific Orbitrap Exploris MX mass detector produces high-resolution accurate mass data for intact analysis of monoclonal antibodies, oligonucleotide mass determination and peptide mapping. The instrument enables drug characterisation processes in QC and productivity improvements by fully integrating the Orbitrap Exploris MX into the multi-attribute method (MAM)2.0 workflow, thereby replacing multiple assays into one mass spectrometric assay. Furthermore, the hardware and software transition from using the Thermo Scientific Orbitrap Exploris 240 mass spectrometer in development stage to using the Orbitrap Exploris MX mass detector in QC stage is made seamless by the compliance-ready Thermo Scientific Chromeleon chromatography data system software.
