On-line chiral reaction monitoring

BrightSpec have introduced the Discovery MRR Diastereomer/Enantiomer analyser for chiral and diastereomer process monitoring. It uses molecular rotational resonance (MRR) spectroscopy, which does not require offline sample preparation, chromatography or chemometrics. The instrument uses a Fabry–Perot cavity for enhanced sensitivity in targeted monitoring. Sample introduction is directly from a continuous synthesis manufacturing process, without prior sample preconditioning, drying or separation. It provides diastereomer and enantiomer quantification in 18 min cycle times and uses argon or neon as carrier gas.