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Bruker has announced its microGRID module for smartbeam 3D MALDI sources for timsTOF fleX systems. The microGRID improves the MALDI stage to sub-micron precision to correct laser positioning on tissue surfaces down to 5 µm, virtually eliminating any visual artefacts or artefacts in co-registration of MALDI images with optical microscopy. As correction is effective for entire pathology slides, microGRID leverages a large field-of-view for MALDI HiPLEX-IHC protein expression profiling.