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Compliance with pharmacopoeia regulations requires that all pharmacological substances have IR spectral data spanning 4000–400 cm–1, the full range usually obtainable on commercially available mid-IR spectrometer systems.
Diamond attenuated total reflection (ATR) accessories like the Quest™ ATR can provide spectral data over the range required by pharmacopoeia. They can replace cumbersome and time-consuming methods employed traditionally for liquid and solid sample analysis in FTIR, such as making KBr pellets or using salt cells.
