SCIEX and Intabio have announced a collaboration to couple Intabio’s Blaze™ system with SCIEX high-resolution accurate mass spectrometers. This integration provides imaged capillary isoelectric focusing with mass spectrometry (iCIEF-MS) in order to simultaneously characterise and identify intact protein charge variants. The successful integration of iCIEF-MS workflows will streamline current laborious and time-consuming approaches in the biopharma environment to identify, monitor and characterise critical quality attributes in intact protein samples for the development and manufacture of next-gen therapeutics.
The commercial release of the Blaze™ system is scheduled for Q4 of 2020 and the integrated iCIEF-MS workflow will be available on SCIEX TripleTOF® 6600+ Systems.