Since the discovery of SERS, researchers have created many types of SERS substrates, with most falling into two categories—colloidal nanoparticles (NPs) and nano-patterned surfaces. Focusing on colloids, several of their features affect the enhancement factor achieved. The size of the NPs and their aggregation are studied in this application note for the optimisation of SERS for glucose sensing. Glucose sensing is important for studying diabetes and investigating the effect of foods in blood glucose levels for both healthy and diabetic people.
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