Scientists at the University of Warwick have developed a computation which simultaneously doubles the resolution, sensitivity and mass accuracy of Fourier Transform Mass Spectrometry (FT-MS) at no extra cost.
Researchers in the University’s Department of Chemistry have solved the 40-year-old phasing problem which allows plotting of spectra in absorption mode. This advance can be used in all FT-MS instruments including FT-ICR, Orbitrap and FT-ToF instruments and will have applications in proteomics, petroleum analysis, metabolomics and pharmaceutical analysis among other fields.
Professor Peter O’Connor, who co-developed the method, said: “We have vastly improved the quality of data available at no extra cost. FTMS is used extensively in the fields of pharmaceuticals, healthcare, industry, natural resources and environmental management so this breakthrough represents a real step towards improving research across the board in these areas.”
The method is detailed in the study “Absorption-Mode: The Next Generation of Fourier Transform Mass Spectra” published in Analytical Chemistry doi: 10.1021/ac3000122). The paper is co-authored by Professor O’Connor, Yulin Qi, Mark Barrow and Huilin Li from the University of Warwick.
Free Webinar
View this Free Webinar
- Most Read
- Highly Rated
- Mass spectrometry investigations of nanoparticles by tandem charge detection mass spectrometry (5 from 9 votes)
- New bulk analysis spectroscopy technique (5 from 6 votes)
- Raman for diabetes monitoring (5 from 6 votes)
- The First Spectroscopic Measurement of an Anti-Atom (5 from 5 votes)
- Fluorescence eye test reveals neurological diseases in livestock (5 from 4 votes)
Latest Comments
-
Gujarathi Dipak B. said More...Sir,
This is an excellent appl... 8 months ago -
Rakesh Kanda said More...Dr Alfonso,
Matrix suppression is ... 1 year ago -
Dr Robson JCF Afonso said More...Dear Authors,
As you sad atmospheric... 1 year ago -
Dr Robson JCF Afonso said More...I am glad to hearing someone question... 2 years ago
-
Peter Jenks said More...That is a reason I\'d overlooked - po... 2 years ago
Contents Alerts
Popular Techniques
- Atomic absorption
- Atomic emission
- Chemometrics
- ICP-MS
- Imaging
- Infrared
- Ion mobility
- Laser spectroscopy
- Luminescencefluorescence
- Mass spectrometry
- Microscopy
- Mobile
- MRI
- Near infrared
- NMR ESR EPR
- Polarimetry
- Process
- Raman
- Related equipment
- RMs and standards
- Sample prep
- Separation science
- Software
- Surface analysis
- Terahertz
- UVvis
- X-ray spectrometry
RSS Feeds
News
Products
Webinars
