Informing Spectroscopists for Over 40 Years

Solid mixed matrices and their advantages in matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry

The bio theme moves to mass spectrometry in “Solid mixed matrices and their advantages in matrix-assisted laser desorption/ionisation time-of-flight mass spectrometry” by Marek Šebela. Getting the most from various matrices for use in matrix-assisted laser desorption/ionisation (MALDI) has always been a bit of an art, and the introduction of mixed matrices may increase the number of possible combinations but may improve reproducibility and so simplify analysis in the end. The author describes mixed matrices for a range of samples including proteins, peptides, oligosaccharides, oligonucleotides, lipids, polymers and even intact microbial cells! 

Content for Registered Users only

  The full content of this page is available to registered and logged-in users only. Please register for free and log in to read it.

Logged-in users have access to our entire archive of articles and columns.